alexa The Influence of Environmental and Genetic Factors on Various Disorders and Diseases
ISSN: 2157-7412

Journal of Genetic Syndromes & Gene Therapy
Open Access

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Review Article

The Influence of Environmental and Genetic Factors on Various Disorders and Diseases

Kadambini Tripathy1*, Tushar Nanda1 and O.V. Sudharani2

1Department of Bioscience and Biotechnology, Fakir Mohan University, Orissa-756020, India

2Centre for Biotechnology, IST, Jawaharlal Nehru Technological University, Hyderabad-500042, India

*Corresponding Author:
Kadambini Tripathy
Department of Bioscience & Biotechnology
Fakir Mohan University, Orissa-756020, India
E-mail: [email protected]

Received date: May 09, 2011; Accepted date:June 13, 2011; Published date: June 15, 2011

Citation: Tripathy K, Nanda T, Sudharani OV (2011) The Influence of Environmental and Genetic Factors on Various Disorders and Diseases. J Genet Syndr Gene Ther S11:001. doi:10.4172/2157-7412.S11-001

Copyright: © 2011 Tripathy K, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Both genetic and environmental factors have been implicated in the mechanism of various disorders. Epidemiological data have shown that environmental factors can also cause and/or exacerbate the pathogenesis of these diseases. However in this article, we provide a summary of evidence for environmental and genetic factors influencing the diseases. The review also incorporates the major findings categorizing the common diseases on the basis of genetic profiles and ethnic information and in establishing personalized disease diagnosis, drug responses and treatment modalities based on the genetic determinants. These studies provide important insights into the interplay between environmental and genetic factors leading to human diseases. Overall an attempt has been made to highlight the importance of studying the genetic profiles of an individual with many factors.

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