alexa The Molecular Biology/Immunology Paradigm Extended to B
ISSN: 2155-9899

Journal of Clinical & Cellular Immunology
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The Molecular Biology/Immunology Paradigm Extended to Bioinformatics

John F. Elder, Steven M. Thompson and Jonghoon Kang*
Department of Biology, Valdosta State University, Valdosta, Georgia 31698, USA
Corresponding Author : Dr. Jonghoon Kang
Assistant Professor, Department of Biology
Valdosta State University, Valdosta, Georgia 31698 USA
Tel: +1 229 333 7140
Fax: +1 229 333 6585
E-mail: [email protected]
Received April 01, 2011; Accepted May 30, 2011; Published August 05, 2011
Citation: Elder JF, Thompson SM, Kang J (2011) The Molecular Biology/ Immunology Paradigm Extended to Bioinformatics. J Clin Cell Immunol 2:111. doi:10.4172/2155-9899.1000111
Copyright: © 2011 Elder JF, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Research progress in any given scientific discipline often relies on the applications of new techniques or the development of new paradigms in related disciplines. Biology, and more specifically immunology, is not an exception to this phenomenon and has historically been particularly driven forward in this manner. Probably one of the best examples of such effects on the life sciences would be the pervasion of molecular biology methodologies and discoveries throughout most biological subdisciplines deriving from the discovery of the structure of DNA made in the early 1950's. At that time DNA structure was a great mystery for the biologists. Prior to the work of Rosalind Franklin, James Watson and Francis Crick, biologists simply did not have the proper tools to solve DNA's structure regardless of their general understanding of the importance of doing so. The structure of the DNA molecule was finally solved by applying a relatively young physics technique, X-ray diffraction [1,2]. The seminal paper on DNA structure published by Watson and Crick [3] provided answers for many questions that had been historically tantalizing, yet irresolvable, to biologists. That paper might be considered as the origin of what was to become the modern molecular biology revolution and the basis for the development of many modern DNA-based biological technologies that have strongly influenced and advanced our understandings in all aspects of current life sciences. Here we briefly examine the development of molecular biology and its implication to the research of immunology, and provide our perspective on the potential role of bioinformatics as a supporting discipline for the future development of immunology.

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