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ISSN: 0974-276X

Journal of Proteomics & Bioinformatics
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Commentary

The Potential for Proteomics in Understanding Neurodevelopmental Disorders

Kelly L Wormwood1, Izabela Sokolowska1, Jeanne P Ryan2, Stephanie Russell2, Costel C Darie2, Alisa G Woods1,2*

1Biochemistry & Proteomics Group, Department of Chemistry & Biomolecular Science, Clarkson University, 8 Clarkson Avenue, Potsdam, NY, 13699-5810, USA

2SUNY Plattsburgh Neuropsychology Clinic and Psychoeducation Services 101 Broad Street, Plattsburgh, NY, 12901, USA

*Corresponding Author:
Alisa G Woods
Biochemistry & Proteomics Group
Department of Chemistry & Biomolecular Science
Clarkson University, 8 Clarkson Avenue
Potsdam, NY, 13699-5810, USA
Tel: (315) 268-7763
Fax: (315) 268-6610
E-mail: [email protected]

Received date: July 27, 2013; Accepted date: September 02, 2013; Published date: September 05, 2013

Citation: Wormwood KL, Sokolowska I, Ryan JP, Russell S, Darie CC, et al. (2013) The Potential for Proteomics in Understanding Neurodevelopmental Disorders. J Proteomics Bioinform S5:001. doi: 10.4172/jpb.S5-001

Copyright: © 2013 Wormwood KL, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

The field of proteomics and use of mass spectrometry as well as other proteomic techniques is continually growing, based on the interest of researchers for searching for potential biomarkers for numerous diseases and disorders. Currently protein biomarkers are not standardly used in clinical practice for diagnosing and monitoring neurodevelopmental disorders. The ability to predict the cause of a medical problem and aid in its treatment would be greatly increased with a biomarker or set of biomarkers. Most studies performed on neurodevelopmental disorders have been in the genomic field rather than in the proteomic realm. However, the few studies that have been performed in proteomics show promise for candidate neurodevelopmental protein biomarkers, both as research tools and in clinical use. Here, we describe potential protein biomarkers for neurodevelopmental disorders and the importance of proteomics in understanding neurodevelopmental disorders.

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