alexa The Potential Therapeutic Usefulness of Targeting BK Polyomavirus in Prostate Cancer
ISSN: 2167-7700

Chemotherapy: Open Access
Open Access

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Commentary

The Potential Therapeutic Usefulness of Targeting BK Polyomavirus in Prostate Cancer

Maurizio Provenzano* and Etienne Xavier Keller

Department of Urology and Division of Surgical Research, University and University Hospital of Zurich, CH-8952 Schlieren, Switzerland

*Corresponding Author:
Maurizio Provenzano
Department of Urology and Division of Surgical
Research, University and University Hospital of Zurich
CH-8952 Schlieren, Switzerland
Tel:
+41-79-8223138
E-mail:
[email protected]

Received Date: December 28, 2015 Accepted Date: January 27, 2016 Published Date: February 04, 2016

Citation: Provenzano M, Xavier Keller E (2015) The Potential Therapeutic Usefulness of Targeting BK Polyomavirus in Prostate Cancer. Chemo Open Access 5:184. doi: 10.4172/2167-7700.1000184

Copyright: © 2016 Provenzano M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Prostate cancer (PCa) is a slow-growing, organ-confined tumor usually accompanied with a favorable overall prognosis. Current standard-of-care chemotherapy, and recently immunotherapies, for patients suffering from this disease may prolong overall survival and improve quality of life, but they do not prevent tumor recurrence and thus are not curative. Underlying reasons are not completely understood. Recent investigations support a possible carcinogenic activity of the human BK polyomavirus (BKPyV) in the prostate. In this commentary, we envisage the development of BKPyV-related therapeutic strategies to be beneficial for individuals at risk of developing PCa.

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