The Relationship between Vitamin D Deficiency and Pulmonary Artery Atherosclerosis in Chronic Thromboembolic Patients
Tarik Kivrak*, Hasan Ata Bolayir, Batur Gonenc Kanar, Dursun Akaslan, Hakan Gunes, Mustafa Oguz and BedrettÄ±n YÄ±ldÄ±zelÄ±
Faculty Tip, Cardiology, Firat University, Turkey
- *Corresponding Author:
- Kivrak T
Faculty Tip, Cardiology
Firat University, Turkey
E-mail: tarik[email protected]
Received Date: May 04, 2017 Accepted Date: May 13, 2017 Published Date: May 22, 2017
Citation: Kivrak T, Bolayir HA, Kanar BG, Akaslan D, Gunes H, et al. (2017) The Relationship between Vitamin D Deficiency and Pulmonary Artery Atherosclerosis in Chronic Thromboembolic Patients. Vitam Miner 6: 159. doi:10.4172/2376-1318.1000159
Copyright: © 2017 Kivrak T, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Background: Our aim of our study was to determine the relationship between vitamin D level and pulmonary artery’s atherosclerosis in patients with chronic pulmonary thromboembolic pulmonary hypertension (CTEPH) who underwent pulmonary endarterectomy (PEA).
Methods: Fifty-six patients with CTEPH who underwent PEA included in our study. Pathologic examination performed to the excised chronic thromboembolic material for the presence of atherosclerosis. We determined patients’ 25-OH vitamin D level in our study.
Results: The average 25-OH vitamin D level in the group of the patients with atherosclerosis was lower than the average 25-OH vitamin D level in the patients with no atherosclerosis (9 ± 6.8 and 16 ± 5.9 pg/ml; p=0.005). There were no significant differences between two groups regarding hypercholesterolemia, high sensitive CRP (hsCRP) and the neutrophile-lymphocyte ratio (N/L ratio).
Conclusions: We believe that vitamin D can be routinely used in patients with CTEPH vitamin D. Vitamin D replacement may be protective against atherosclerosis in these patients.