alexa The Reproductive Health and Liver Functions of Occupati
ISSN: 2161-0495

Journal of Clinical Toxicology
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Research Article

The Reproductive Health and Liver Functions of Occupationally Exposed Female Pesticide Sprayers of Mango Plantations

Farrukh Jamal* and Quazi S. Haque*
Department of Biochemistry, Dr. Ram Manohar Lohia Avadh University, Faizabad-224001, India
*Corresponding Authors : Dr. Farrukh Jamal
Assistant Professor
Department of Biochemistry
Dr. Ram Manohar Lohia Avadh University
Faizabad-224001, India
E-mail: [email protected]
  Quazi S. Haque
Dr. Ram Manohar Lohia Avadh University
Faizabad-224001, U.P, India
Fax: +91-05278-246330
E-mail: [email protected]
Received: December 18, 2015; Accepted: February 02, 2016; Published: February 12, 2016
Citation: Jamal F, Haque QS (2016) The Reproductive Health and Liver Functions of Occupationally Exposed Female Pesticide Sprayers of Mango Plantations. J Clin Toxicol 6:279. doi:10.4172/2161-0495.1000279
Copyright: © 2016 Jamal F, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


The present study explores the effect of pesticide exposure on the reproductive health and liver function of females participating in agricultural related work. Blood samples were obtained from thirty-five (35) females (out of one hundred females of reproductive age) who were willing donors. Fifty (50) females matched for age and socio economic status was recruited as a control group to compare levels of hormones (estradiol, progesterone and follicle stimulating hormone), liver enzymes-alanine aminotransferase (ALT), and aspartate aminotransferase (AST). Results showed that 56% of the females were illiterate with 48% representing agricultural work. Females who helped in farming operations showed a higher incidence of adverse pregnancy outcome such as abortions and stillbirths compared to non-participants. There was a significant elevation in estradiol and progesterone levels among female agricultural workers. While there was an elevation in serum liver enzymes (AST and ALT) there was a significant decrease in FSH level in females engaged in agricultural activities. The study suggests that participation of females in agricultural activities with potential exposure to pesticides endangers their reproductive health and liver functions.


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