alexa The Research Progress of Long Noncoding RNAs in Autoimm
ISSN: 2155-9562

Journal of Neurology & Neurophysiology
Open Access

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Review Article

The Research Progress of Long Noncoding RNAs in Autoimmune Diseases

Li Zou, Md Rezaul Karim and Yun-fu Wang*

Department of Neurology, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei 442000, P. R. China

*Corresponding Author:
Yun-fu Wang
Department of Neurology, Taihe Hospital
Hubei University of Medicine, Shiyan
Hubei 442000, P. R. China
E-mail: [email protected]

Received date: January 18, 2016 Accepted date: March 09, 2016 Published date: March 16, 2016

Citation: Zou L, Karim RM, Wang YF (2016) The Research Progress of Long Noncoding RNAs in Autoimmune Diseases. J Neurol Neurophysiol 7:359. doi:10.4172/2155-9562.1000359

Copyright: © 2016 Karim RM, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Long Noncoding RNAs (lncRNAs) are transcribed RNAs molecules greater than 200 nucleotides in length. Nowadays, lncRNAs are found to have lots of functions including regulating transcription, post-transcriptional RNA processing, translation, gene rearrangement and chromatin modification. Abnormal expressions and functional abnormity of lncRNAs may play an important role in the development and progress of autoimmune diseases. Thus a systematic and comprehensive profiling of lncRNA will help us to have a deeper understanding of the pathogenesis of the diseases. This article will focus on the latest research progress of lncRNA in autoimmune diseases, which will contribute to clinical applications for diagnosis, prognosis and treatment of autoimmune diseases.

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