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ISSN: 2155-9880

Journal of Clinical & Experimental Cardiology
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Review Article

The Right Heart in Congenital Heart Disease, Mechanisms and Recent Advances

Julien Guihaire1*,#, François Haddad2#, Olaf Mercier3, Daniel J. Murphy4, Joseph C. Wu5 and Elie Fadel6
1Cardiac Surgeon, Universite Paris-Sud, Laboratory of Surgical Research, Marie Lannelongue Surgical Center, France
2Assistant Clinical Professor of Medicine, Stanford University, USA
3Attending Surgeon, Universite Paris-Sud, Laboratory of Surgical Research, Marie Lannelongue Surgical Center, France
4Professor of Pediatrics, Stanford University, USA
5Associate Professor of Medicine and Radiology, Stanford University, USA
6Professor of Surgery, Universite Paris-Sud, Laboratory of Surgical Research, Marie Lannelongue Surgical Center, France
#Both Julien Guihaire and Francois Haddad contributed equally to the article
Corresponding Author : Julien Guihaire, MD MSc.
Centre Chirurgical Marie Lannelongue
Universite Paris-Sud, France
E-mail: [email protected]
Received December 14, 2011; Accepted April 30, 2012; Published June 15, 2012
Citation:Guihaire J, Haddad F, Mercier O, Murphy DJ, Wu JC, et al. (2012) The Right Heart in Congenital Heart Disease, Mechanisms and Recent Advances. J Clin Exp Cardiolog S8:010. doi:10.4172/2155-9880.S8-010
Copyright: © 2012 Guihaire J, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Abstract

In patients with congenital heart disease, the right heart may support the pulmonary or the systemic circulation. Several congenital heart diseases primarily affect the right heart including Tetralogy of Fallot, transposition of great arteries, septal defects leading to pulmonary vascular disease, Ebstein anomaly and arrhythmogenic right ventricular cardiomyopathy. In these patients, right ventricular dysfunction leads to considerable morbidity and mortality. In this paper, our objective is to review the mechanisms and management of right heart failure associated with congenital heart disease. We will outline pearls and pitfalls in the management of congenital heart disease affecting the right heart and highlight recent advances in the field.

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