alexa The Role of Fetal Neurology in the Progress of Perinatal Medicine
ISSN: 2157-7420

Journal of Health & Medical Informatics
Open Access

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Research Article

The Role of Fetal Neurology in the Progress of Perinatal Medicine

Ritsuko K Pooh*

CRIFM Clinical Research Institute of Fetal Medicine PMC, Osaka, Japan

*Corresponding Author:
Ritsuko K Pooh
CRIFM Clinical Research Institute of Fetal Medicine PMC 7-3-7, Uehommachi, Tennoji, Osaka City
#543-0001, Osaka, Japan
Tel: +81-6-6775-8111
Fax: +81-6-6775-8122
E-mail: [email protected]

Received date: June 12, 2013; Accepted date: June 25, 2013; Published date: June 30, 2013

Citation: Pooh RK (2013) The Role of Fetal Neurology in the Progress of Perinatal Medicine. J Health Med Informat S11:015. doi: 10.4172/2157-7420.S11-015

Copyright: © 2013 Pooh RK. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



The prevalence of cerebral palsy has not decreased despite major improvements in clinical care in antenatal/
neonatal period as well as intrapartum period. In about 70% of cases, cerebral palsy results from events occurring
before birth that can disrupt normal development of the brain. The antepartum risk factors should include fetal brain
mal development and intrauterine brain injuries, which are unclassifiable into congenital brain anomalies and may exist
inconspicuously during pregnancy and even after birth. Especially, neuronal migration disorder and acquired brain
damage in utero should be responsible for postnatal neurological impairment. Imaging technologies including three
dimensional ultrasound have been remarkably improved and contributed to prenatal evaluation of fetal Central Nervous
System (CNS) development and assessment of CNS abnormalities in utero. In this article, objective and precise imaging
diagnoses of fetal CNS including migration disorders and acquired brain damages. Furthermore, 3D bidirectional power
Doppler angiography has depicted fine cerebral vessels of medullary veins which may relate with timing of insult as well
as with postnatal neurological prognosis. It is promising to clarify the developmental mechanism of CNS damages with
advanced ultrasound diagnostic techniques in the near future. Postnatal unexplained neurological deficits may strongly
relate with intrauterine brain development therefore fetal neurology has great responsibility and an important role in
perinatal medicine.


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