The Role of Helminths in Immunity
- *Corresponding Author:
- Goyal K
Department of Medical Parasitology
Postgraduate Institute of Medical Education & Research
Chandigarh - 160 012, India
E-mail: [email protected]
Received date: January 13, 2016 Accepted date: February 11, 2016 Published date: February 18, 2016
Citation: Deepak T, Goyal K (2016) The Role of Helminths in Immunity. J Allergy Ther 7:231. doi:10.4172/2155-6121.1000231
Copyright: © 2016 Deepak T, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Helminths modulate both the adaptive and innate arms of human immune system. Such immune alteration seems to have an anti-inflammatory effect. Chronic helminth infections switch the immune response from Th1 to Th2 by various mechanisms and by different helminth derived molecules. Though these immunological responses provide a survival advantage, they seem to hamper the response to non-helminth derived antigens. Immune response to oral vaccines and many auto-immune disorders are influenced by immunomodulatory effects of helminths. As a part of eukaryotic community in the gut, helminths might have a potential role in the development of immune system.