alexa The Role of Hemodialysis and Fomepizole in Ethylene Glycol Intoxication | OMICS International | Abstract
ISSN: 2161-0959

Journal of Nephrology & Therapeutics
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Research Article

The Role of Hemodialysis and Fomepizole in Ethylene Glycol Intoxication

Gregory K. Buller*, Craig B. Moskowitz and Karen Eckardt
Department of Internal Medicine, Saint Mary’s Hospital, Waterbury, Connecticut, USA
Corresponding Author : Gregory K. Buller
Department of Internal Medicine
Saint Mary’s Hospital, Waterbury, Connecticut, USA
E-mail: [email protected]
Received March 30, 2012; Accepted May 19, 2012; Published May 21, 2012
Citation: Buller GK, Moskowitz CB, Eckardt K (2012) The Role of Hemodialysis and Fomepizole in Ethylene Glycol Intoxication. J Nephrol Therapeutic S10:004. doi:10.4172/2161-0959.S10-004
Copyright: ©2012 Buller GK, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Calciphylaxis or calcific uremic arteriolopathy is a relatively uncommon condition with poor prognosis. Although it is predominantly observed in patients with end stage renal disease, a few cases of patients without kidney failure have been reported. Calciphylaxis is characterized by calcification of the arteriolar intima media and eventually by vascular thrombosis, tissue ischemia and painful skin necrosis. Septicemia is the main cause of death. According to published literature concerning the pathology of calciphylaxis, prevention and treatment are principally based on interventions in calcium and phosphorus metabolism. Although novel therapies have emerged, due to the rarity of this condition, there is no sufficient data in favor of a certain treatment.

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