alexa The Role of NADPH Oxidases in Cardiovascular Disease
ISSN: 2329-6925

Journal of Vascular Medicine & Surgery
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Review Article

The Role of NADPH Oxidases in Cardiovascular Disease

Zhang W1, Bai J1, Tian J1, Jia L2and Zhou X1*

1Department of Cardiology, The First Affiliated Hospital of Harbin Medical University, Harbin, PR China

2Department of Clinical Laboratory, General Hospital of Daqing Oil Field, Daqing, PR China

Corresponding Author:
Zhou X
Department of Cardiology
The First Affiliated Hospital of Harbin Medical University, Harbin
Heilongjiang, 150001, PR China
Tel: 086-0451-85555686

Received March 06, 2016; Accepted April 25, 2016; Published May 03, 2016

Citation: Zhang W, Bai J, Tian J, Jia L, Zhou X (2016) The Role of NADPH Oxidases in Cardiovascular Disease. J Vasc Med Surg 4:265. doi:10.4172/2329- 6925.1000265

Copyright: © 2016 Zhang W, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




Cardiovascular disease is the high incidence of disease in the world and has the high rate of mortality and morbidity. Therefore, researching new mechanisms of cardiovascular disease has been received the widespread attention. A large number of studies have shown that oxidative stress is one of the main mechanisms of cardiovascular disease occurrence and development. Excessive reactive oxygen species cause an imbalance in the body of oxidation and anti-oxidation, which causes tissue damage. NADPH oxidase is the principal source of reactive oxygen species, thereby, studying clearly the role of NADPH oxidase in cardiovascular disease has important clinical significance for preventing and treating cardiovascular diseases via controlling oxidative stress. We summarized the newest studies on the relationship between NADPH Oxidases and cardiovascular diseases, which provide an idea that NADPH Oxidases play an important role in cardiovascular disease occurrence and development. This idea may illustrate the new cardiovascular disease pathogenesis and discovering new methods for cardiovascular diseases prevention and treatment.


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