The Structure of the Electric Double Layer of Macromolecules Suspended in Human Cerebrospinal FluidLeszek Herbowski1* and Henryk Gurgul2
- Corresponding Author:
- Dr. Leszek Herbowski
Public Provincial Hospital
Arkonska 4, 71-455 Szczecin, Poland
E-mail: [email protected]
Received date: December 27, 2010; Accepted date: February 12, 2011; Published date: February 16, 2011
Citation: Herbowski L, Gurgul H (2011) The Structure of the Electric Double Layer of Macromolecules Suspended in Human Cerebrospinal Fluid. J Neurol Neurophysiol 2:108. doi:10.4172/2155-9562.1000108
Copyright: © 2011 Herbowski L, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
The cerebrospinal fluid is a dilute suspension of large colloidal macroparticles such as protein molecules and cells. Based on microscopic observations of cerebrospinal fluid samples and some theoretical data the authors could develop a schematic structure of electric double layer around the biomolecules suspended in cerebrospinal fluid. Numerical results show that the averaged diameter of the observed macroparticles is 5,1 μm. We could observe Brownian motions of large biomolecules as a result of thermal nanoparticles movements. Understanding ions composition of cerebrospinal fluid we could state that the compact Stern layer consists of sodium cations and the Gouy layer of chloride anions. Our calculations reveal that the thickness of the Stern layer surrounding macroparticles in cerebrospinal fluid is 0,366 nm.