alexa The Study of Cold Stress - Induced Changes in Rat Mesovarium's Mast Cell Size and Structure in Relation with Estrous Cycle | OMICS International| Abstract
ISSN: 2157-7099

Journal of Cytology & Histology
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  • Research Article   
  • J Cytol Histol 2019, Vol 10(1): 529
  • DOI: 10.4172/2157-7099.1000529

The Study of Cold Stress - Induced Changes in Rat Mesovarium's Mast Cell Size and Structure in Relation with Estrous Cycle

Tumenbayar B*, Tumenbayar B1*, Tsolmon D1, Suvdaa B2, Enkhzul B2, Chimegsaihan S2, Altangadas D2, Naranbat B2, Munkhzol M2 and Bayarmaa E2
1Department of Histology, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia
2Laboratory of Pathology, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia
*Corresponding Author : Tumenbayar B, Department of Histology, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia, Tel: +976-99192441, Email: [email protected]

Received Date: Jan 18, 2019 / Accepted Date: Jan 28, 2019 / Published Date: Jan 31, 2019

Abstract

The climate of Mongolia is dry and extreme, with cold seasons during the 5-7 months of year, which is one of the causes of cold-borne disorders occurring in people. In our country, there are cases of women with inflammatory disease of reproductive organ too. Although the researches on ovarian mast cells have been common so far, the researches on mesovarium mast cells, which have good blood and nerve supply, are pretty uncommon. The researches on cold stress induced changes in mesovarium mast cells’ number, size and structure in relation with menstrual cycle hasn’t been done yet in our country. In our study, we have chosen 16 rats in control group and 48 rats in cold stress group, a total of 64 rats. The cold stress group was divided again into 3 groups (16:16:16) and underwent daily cold stress (refrigerator-15°C) from 8:00 am-11:00 am for 7, 14, 21 days in order to generate cold stress model. The number, shape, structural changes, size, perimeter, length and width of the mesovarium mast cell were determined. The determination of estrous cycles was carried out at 8 am on test day by taking a smear from the vagina using Papanicolaou test and the phases of estrous cycle was determined by histological test.

Keywords: Mast cell; Estrous cycle; Cold stress

Citation: Tumenbayar B, Tsolmon D, Suvdaa B, Enkhzul B, Chimegsaihan S, et al. (2019) The Study of Cold Stress - Induced Changes in Rat Mesovarium’s Mast Cell Size and Structure in Relation with Estrous Cycle. J Cytol Histol 10: 529. Doi: 10.4172/2157-7099.1000529

Copyright: © 2019 Tumenbayar B, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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