alexa The Study of Novel Sulfilimines as Potential Insects Modulators | OMICS International| Abstract

ISSN: 2161-0398

Journal of Physical Chemistry & Biophysics

  • Research Article   
  • J Phys Chem Biophys 2015, Vol 5(1): 174
  • DOI: 10.4172/2161-0398.1000174

The Study of Novel Sulfilimines as Potential Insects Modulators

Sha Zhou and Zhengming Li*
State Key Laboratory of Elemento-Organic Chemistry, Institute of Elemento-Organic Chemistry, College of Chemistry, Nankai University, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin 300071, China
*Corresponding Author : Zhengming Li, State Key Laboratory of Elemento-Organic Chemistry, Institute of Elemento-Organic Chemistry, College of Chemistry, Nankai University, Collaborative Innovation Center Of Chemical Science And Engineering, (Tianjin), Tianjin 300071, China, Tel: 8602223503703, Email: [email protected]

Received Date: Dec 15, 2014 / Accepted Date: Feb 06, 2015 / Published Date: Feb 09, 2015

Abstract

This paper describes the novel sulfiliminyl structures as potential control of the Ca2+ influx within the Ryanodine Receptor of insect body. Referring to commercial Flubendiamide structural composition, N-cyano, N-trifluroacetyl and N-acylamino sulfiliminyl moieties were firstly introduced into dicarboxamides scaffolds. The chiral sulfilimines especially exhibited significant insecticidal activities. The investigation of chirality impact on bioactivity was also systemically studied.

Keywords: Insecticides; Sulfilimines; Ryanodine receptor; Chirality

Citation: Zhou S, Li Z (2015) The Study of Novel Sulfilimines as Potential Insects Modulators. J Phys Chem Biophys 5: 174. Doi: 10.4172/2161-0398.1000174

Copyright: © 2015 Zhou S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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