Thyroid Antibody Associated Recurrent Spontaneous Abortion
|Radhika Tirumala1 and Rosalind A Hayes2*|
|1 Resident Physician, Obstetrics and Gynecology Residency Program, Rochester General Hospital, Rochester, New York, USA|
|2 Clinical Assistant Professor of OB/GYN, Rochester Fertility Care, University of Rochester, PC, Rochester, New York, USA|
|*Corresponding Author :||Rosalind A Hayes, MD
Clinical Assistant Professor of OB/GYN
Rochester Fertility Care, University of Rochester
PC, Rochester, New York 14626, USA
E-mail: [email protected]
|Received February 13, 2014; Accepted June 10, 2014; Published June 12, 2014|
|Citation: Tirumala R, Hayes RA (2014) Thyroid Antibody Associated Recurrent Spontaneous Abortion. J Fertil In Vitro IVF Worldw Reprod Med Genet Stem Cell Biol 2:126. doi:10.4172/jfiv.1000126|
|Copyright: © 2014 Tirumala R, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.|
Background: Recurrent spontaneous abortion (RSA) remains unexplained in about 50% of cases after a
standard evaluation. A subset of unexplained RSA may be thyroid antibody associated recurrent spontaneous abortion (TAARSA).
Cases: The three cases illustrate TAARSA with elevated thyroid antibodies and a euthyroid state. Treatment with low molecular weight heparin (LMWH) and low dose aspirin (LDA) was associated with live birth.
Conclusions: A subset of previously unexplained RSA may be identified as TAARSA. Treatment may prevent
future pregnancy loss.