alexa Thyrotoxic Periodic Paralysis
ISSN: 2165-7920

Journal of Clinical Case Reports
Open Access

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Case Report

Thyrotoxic Periodic Paralysis

Nimat Alam*, Linda Esteban, Enrique Tobias and Jenet George

Department of Family and Community Medicine, Texas Tech University Health Science Center, USA

Corresponding Author:
Nimat Alam
Department of Family and Community Medicine
Texas Tech University Health Science Center, USA
Tel: +1 806-743- 1000
E-mail: [email protected]

Received date: May 31, 2016; Accepted date: July 23, 2016; Published date: July 28, 2016

Citation: Alam N, Esteban L, Tobias E, George J (2016) Thyrotoxic Periodic Paralysis. J Clin Case Rep 6:839. doi:10.4172/2165-7920.1000839

Copyright: © 2016 Alam N, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Thyrotoxic periodic paralysis (TPP) is characterized by abrupt onset of hypokalemia and paralysis. This condition primarily affects the lower extremities but may affect both upper and lower extremities and is secondary to thyrotoxicosis. It is most commonly seen in Asian men and it has been increasingly reported in USA due to the rise in the immigrant population. Hypokalemia in TPP results from an intracellular shift of potassium induced by the thyroid hormone sensitization of Na+/K+ATPase rather than depletion of total body potassium.


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