Towards Biological Target Volumes Definition for Radiotherapy Treatment Planning: Quo Vadis PET/CT?Slobodan Devic*
Department of Radiation Oncology, Jewish General Hospital, McGill University, Montreal, Quebec, Canada
- *Corresponding Author:
- Slobodan Devic
SMBD Jewish General Hospital
3755 chemin de la Cote-Sainte-Catherine
Montreal, Quebec H3T 1E2, Canada
Tel: 514 340 82222595
E-mail: [email protected]
Received date: June 26, 2013; Accepted date: July 25, 2013; Published date: July 29, 2013
Citation: Devic S (2013) Towards Biological Target Volumes Definition for Radiotherapy Treatment Planning: Quo Vadis PET/CT? J Nucl Med Radiat Ther 4:158. doi:10.4172/2155-9619.1000158
Copyright: © 2013 Devic S. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
This paper reviews efforts of incorporating FDG based PET/CT data into target volume delineation for radiotherapy treatment planning. Relationship between PET-based and CT-based volumes generally suffer from poor correlation between the two image data sets, expressed in terms of large statistical variation in gross tumor volume ratios irrespective of the thresholding method used. Future of biologically tailored target volumes for radiotherapy treatment planning might not be the replacement of CT or MRI based anatomical gross tumor volumes by PET based volumes. Instead, the two target volumes should complement each other into a complex mosaic of biological target volumes.