Transcranial Direct Current Stimulation (tDCS) for Panic Disorder: A Case Study
|Pedro Shiozawa*, Mailu Enokibara da Silva and Quirino Cordeiro|
|The Clinical Neuromodulation Laboratory, Santa Casa Medical School, São Paulo, Brazil|
|*Corresponding Author :||Pedro Shiozawa
Department of Psychiatry
Santa Casa Medical School
Rua Major Maragliano, 241
Vila Mariana, ZIP: 0460001, São Paulo, Brazil
E-mail: [email protected]
|Received April 23, 2014; Accepted May 27, 2014; Published May 31, 2014|
|Citation: Shiozawa P, da Silva ME, Cordeiro Q (2014) Transcranial Direct Current Stimulation (tDCS) for Panic Disorder: A Case Study. J Depress Anxiety 3:158. doi:10.4172/2167-1044.1000158|
|Copyright: © 2014 Shiozawa P, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.|
Background: Panic disorder (PD) is characterized primarily by the presence of recurrent and unexpected panic attacks, followed by at least one month of persistent concern about other attacks, the possible consequences of attacks and a significant behavioral change related to the attacks. The neurocircuitry of fear includes two pathways for processing of sensory information. Transcranial direct current stimulation (tDCS) use has not been reported for PD.
Objective: To report the results of an experimental tDCS protocol for ameliorating anxiety symptoms in a patient with panic disorder.
Method: The current report is based on a single case study. We used an experimental tDCS intervention protocol as to inhibit the right dorsolateralprefrontal cortex during a period of two weeks. Symptoms were assessed by adequate clinical scales.
Results: We hereby describe a 44-year-old woman with PD who successfully underwent a tDCS intervention, with important ameliorating of her symptoms.
Discussion and Conclusion: To the best of our knowledge, this it is the first report using tDCS for PD. Some study limitations, however, should be addressed. Our findings are based on a case study, thus having limited generalizability. Nonetheless, these encouraging results should be seen as hypothesis-driving for further controlled, randomized trials exploring the impact of tDCS in the treatment of PD and maybe other anxiety disorders.