Transcriptional Profiling of Stress Response or Slow Growth?Zhang X1 and Liu J1,2*
- *Corresponding Author:
- Jianhua Liu
Professor, Ocean College, Zhejiang University
Zhoushan Campus, Marine Science Building #379
1 Zheda Road, Dinghai District, Zhoushan
ZJ 316000, China
E-mail: [email protected]
Received date: May 09, 2017; Accepted date: May 10, 2017; Published date: May 16, 2017
Citation: Zhang X, Liu J (2017) Transcriptional Profiling of Stress Response or Slow Growth? Metabolomics (Los Angel) 7:e153. doi: 10.4172/2153-0769.1000e153
Copyright: © 2017 Zhang X, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Transcriptomic profiling analyses are frequently used for the study of cells in response to environmental stress factors that often impede cell optimal growth. Given that transcriptional profiles of optimally growing cells differ significantly from those of sub-optimally growing cells, stress-induced differentially-transcribed genes are thus inevitably mixed with slow growth genes. It is therefore necessary to separate the stress-specific response genes from slow growth genes. Methodologies used to deconvolute stress-specific response from non-specific response such as slow growth are discussed in this editorial.