alexa Transplantation of Enteric Cells into the Rodent Stomach with Basic Fibroblast Growth Factor
ISSN: 2157-7013

Journal of Cell Science & Therapy
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Transplantation of Enteric Cells into the Rodent Stomach with Basic Fibroblast Growth Factor

Carrie L. Geisbauer1, June C. Chapin3, Benjamin M. Wu1,2,4 and James C.Y. Dunn1,2,3*
1Biomedical Engineering Interdepartmental Program, University of California, Los Angeles, CA
2Department of Bioengineering, University of California, Los Angeles, CA
3Department of Surgery, Division of Pediatric Surgery, University of California, Los Angeles, CA
4Department of Material Science and Engineering, University of California, Los Angeles, CA
Corresponding Author : James C.Y. Dunn, M.D., Ph.D
UCLA Surgery-Pediatrics, Box 957098
CHS 72-140, Los Angeles, CA 90095-7098
Tel: 310.206.2429
Fax: 310.206.1120
E-mail: [email protected]
Received November 23, 2010; Accepted March 09, 2011; Published March 10, 2011
Citation: Geisbauer CL, Chapin JC, Wu BM, Dunn JCY (2011) Transplantation of Enteric Cells into the Rodent Stomach with Basic Fibroblast Growth Factor. J Cell Sci Ther 2:103. doi: 10.4172/2157-7013.1000103
Copyright: © 2011 Geisbauer CL, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
 

Abstract

Enteric cells, isolated from intestinal smooth muscle strips, were transplanted into the syngeneic rodent stomach in collagen gel with and without basic fibroblast growth factor (bFGF). While growth factor delivery did not affect cell viability after transplantation, bFGF promoted the formation of numerous ganglion-like structures at the injection site and adjacent muscularis. Immunohistochemistry staining revealed the presence of peripherin, S100, and synaptophysin in these ganglion-like structures. A small percentage of transplanted enteric cells expressed peripherin in the injection site after transplantation. Enteric cells transplanted with collagen and bFGF may hold potential as a cellular therapeutic for various motility disorders of the gastrointestinal tract.

Keywords

Share This Page

Additional Info

Loading
Loading Please wait..
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords