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ISSN: 2161-0932

Gynecology & Obstetrics
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Review Article

Treatment of Pre-eclampsia: Implementing Research Findings

S.V. Ramesar1*, P. Gathiram2, J. Moodley3 and I Mackraj3

1Department of Physiology and Physiological Chemistry, University of KwaZulu-Natal, Durban, South Africa

2Department of Family Medicine, Nelson R Mandela School of Medicine, University of KwaZulu- Natal, Durban, South Africa

3Department of Obstetrics and Gynaecology and Women’s Health and HIV Research Unit, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa

Corresponding Author:
Shamal Vinesh Ramesar
Department of Physiology and Physiological Chemistry
University of KwaZulu-Natal, Private Bag X5400
Durban, South Africa
Fax: (+27)31 – 260 7132
E-mail: [email protected]

Received Date: December 02, 2011; Accepted Date: April 12, 2012; Published Date: April 17, 2012

Citation: Ramesar SV, Gathiram P, Moodley J, Mackraj I (2012) Treatment of Pre-eclampsia: Implementing Research Findings. Gynecol Obstetric 2:117. doi: 10.4172/2161-0932.1000117

Copyright: © 2012 Ramesar SV, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited

Abstract

Pre-eclampsia is a complex disease that affects both mother and their developing fetus. Due to the multifactorial nature of the disease and its undeciphered etiology, we explore the possibility of improving intrinsic vasodilatory mechanisms as a method of treatment. Reduced utero-placental blood flow seems to be central in the manifestation of this disease leading to the secretions of various factors that maintain and/or worsen the condition. We and various other researchers have showed that improved placental perfusion shows promise in alleviating many symptoms of the disease. This serves as an excellent option at reducing both perinatal and maternal morbidity and mortality irrespective of the predisposing factors for the disease.

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