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ISSN: 2167-1052

Advances in Pharmacoepidemiology and Drug Safety
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Research Article

Trends in Antihypertensive Drug Use in Spanish Primary Health Care (1990-2012)

Cáceres MC1, Moyano P1, Fariñas H1, Cobaleda J1,2, Pijierro A1, Dorado P1and LLerena A1*
1CICAB Clinical Research Centre, Extremadura University Hospital and Medical School, Badajoz, Spain
2Ciudad Jardin Primary Health Care Center.SES Servicio Extremeño de Salud, Badajoz, Spain
*Corresponding Author : LLerena A
CICAB, Clinical Research Centre
Extremadura University Hospital and Medical School
Badajoz 06080, Spain
Tel: +34924218040
Fax: +34924289675
E-mail: [email protected]
Received November 05, 2014; Accepted January 05, 2015; Published January 06, 2015
Citation: Cáceres MC, Moyano P, Fariñas H, Cobaleda J, Pijierro A, Darado P,LLerena A (2015) Trends in Antihypertensive Drug Use in Spanish Primary Health Care (1990-2012). Adv Pharmacoepidemiol Drug Saf 3:172. doi:10.4172/2167-1052.1000172
Copyright: © 2015 Cáceres MC, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Objective: This study aimed to describe the use of antihypertensive in Extremadura (Spain) from 1990 to 2012 and its economic impact.
Method: Information on antihypertensive drug (ATC C02, C03, C07, C08, C09) utilization was obtained from the community pharmacy sales figures reimbursed by the Health System of Extremadura (Spain). Data were expressed in Defined Daily Dose (DDD) and DDD per 1000 inhabitants per day (DHD).
Results: Antihypertensive consumption in Extremadura increased from 67.1 DHD in 1990 to 315.2 in 2012 (an increase of 3.7 times). Agents acting on the Renin-Angiotensin System (C09) are responsible for 75% of the total increase. Since 2007 the use of Angiotensin II antagonist increased over ACE inhibitors.
Conclusions: The consumption of antihypertensive drugs in Extremadura increased remarkably in the last 23 years. In the last years the use of angiotensin II antagonist drugs is having a significant economic impact.

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