alexa Trigeminal Sensory Neuropathy in Mixed Connective Tissue Disease | OMICS International | Abstract
ISSN: 2155-9562

Journal of Neurology & Neurophysiology
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Trigeminal Sensory Neuropathy in Mixed Connective Tissue Disease

Sharika Rajan1, Rajesh Gupta1, Maria J Borja2, Naina Rastalksy3, Nagagopal Venna1 and Dinesh G Nair1*

1Department of Neurology, Massachusetts General Hospital, USA

2Department of Radiology, Massachusetts General Hospital, USA

3Department of Rheumatology, Massachusetts General Hospital, USA

*Corresponding Author:
Dinesh G Nair
Department of Neurology
Massachusetts General Hospital
15 Parkman St., Boston MA 02114-3117, USA
Tel: 617-726-3642
Fax: 617-726-2019
E-mail: [email protected]

Received date: October 03, 2016; Accepted date: October 04, 2016; Published date: October 07, 2016

Citation: Rajan S, Gupta R, Borja MJ, Rastalksy N, Venna N, et al. (2016) Trigeminal Sensory Neuropathy in Mixed Connective Tissue Disease. J Neurol Neurophysiol 7:i106. doi: 10.4172/2155-9562.1000i106

Copyright: © 2016 Rajan S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

A 23 year old woman presented to the clinic with Raynaud's phenomenon and numbness and tingling in her right cheek, chin and the right side of her tongue. Examination showed altered facial sensation to touch and pinprick in the right V1-V3 distributions. When investigations revealed that her ANA was 1:5120 in a speckled pattern and anti- RNP was 243.79 U, a diagnosis of Mixed Connective Tissue Disease (MCTD) was made. MRI brain showed diffuse enhancement of the Trigeminal nerves bilaterally, right>left. Trigeminal sensory neuropathy is the most common CNS manifestation of MCTD and often the presenting symptom. Prognosis is variable, some features respond to glucocorticoids.

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