Two Weeks of Low Dose Fish Oil Supplementation Followed By A Single Bout of Exercise Increases High Density Lipoprotein Cholesterol in College-Aged and Middle-Aged MenRachael M Thomas, Edward Meadors, Caroline Pilgrim, Hannah Johnson, Maria Smith, David C Ianuzzo and Richard C Baybutt*
Applied Health Science Department, Wheaton College, Wheaton, IL, USA
- *Corresponding Author:
- Richard C Baybutt
Applied Health Science Department
Wheaton College, 501 College Ave., Wheaton, IL 60187 USA
E-mail: [email protected]
Received date: May 29, 2013; Accepted date: July 22, 2013; Published date: July 24, 2013
Citation: Thomas RM, Meadors E, Pilgrim C, Johnson H, Smith M, et al. (2013) Two Weeks of Low Dose Fish Oil Supplementation Followed By A Single Bout of Exercise Increases High Density Lipoprotein Cholesterol in College-Aged and Middle-Aged Men. J Nutr Food Sci 3:221. doi:10.4172/2155-9600.1000221
Copyright: © 2013 Thomas RM, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
There is a significant inverse relationship between high density lipoprotein cholesterol (HDL-C) and cardiovascular events. Previous studies have reported increased HDL-C in response to 4 weeks of pharmacological doses of omega-3 fatty acids (n-3 FA) (3-5g/day). Our hypothesis was that a low dose of n-3 FA (eicosapentaenoic and docosahexaenoic acid), one achievable in the diet, ingested in the form of one fish oil capsule three times per day by college-aged and middle-aged men, over a short period of 2 weeks, preceded and followed by a single bout of exercise, would increase HDL-C levels. We determined serum lipid profile (triglyceride, VLDL-C, LDL-C, HDL-C, total cholesterol) in response to a single bout of exercise (60 min, 55-60% HRmax) after consuming a low dose of 0.9 g n-3 FA/day for 14 days in eight middle-aged men (age 48.9 ± 1.4) and seven college-aged men (age 21 ± 2.5). There were no significant changes with blood lipids except in HDL-C. In middle-aged and college-aged men HDL-C significantly increased (P<0.005). The college-aged men’s TC/HDL-C ratio significantly increased (P<0.05). Our findings suggest that two weeks of ingesting dietary achievable doses of n-3 FA followed by a single bout of exercise increase HDL-C, which is associated with a decreased risk for coronary heart disease (CHD).