Two Young Men with Leonine Facies and Generalized Itching - Two Case Reports of Sezary SyndromeAkter M1*, Khan MA2, Afrose S1, Ara T1, Ferdous J1 and Islam MM1
- *Corresponding Author:
- Akter M
Department of Haematology
Dhaka Medical College Hospital, Dhaka, Bangladesh
Tel: 88 01912112724
Received date: October 14, 2014; Accepted date: November 21, 2014; Published date: November 28, 2014
Citation: Akter M, Khan MA, Afrose S, Ara T, Ferdous J, et al. (2014) Two Young Men with Leonine Facies and Generalized Itching - Two Case Reports of Sezary Syndrome. J Integr Oncol 3:123. doi:10.4172/2329-6771.1000123
Copyright: © 2014 Akter M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Two male aged 37 years and 29 years presented with generalized itching followed by thickening and reddening of whole body for 3 and 6 months respectively. On examination generalized erythroderma, lymphadenopathy and hepato-splenomegaly were found. In both cases leucocyte count was high and of which 80-90% were morphologically Sezary cells. Peripheral blood absolute CD4+ lymphocytes were very high in both the cases. Skin biopsy showed dense infiltrate of lymphocytes in the dermis with intraepidermal collection of lymphocytes. Bone marrow was infiltrated with Sezary cells.