Ultra-Low Dose Cardiac CT Angiography at 80 kV using Second Generation Dual-Source CT: Assessment of Radiation Dose and Image Quality
|Leif-Christopher Engel1*, Maros Ferencik1, Gary Y. Liew1, Mihaly Karolyi1, Manavjot S Sidhu1, Ashley Mingshin Lee1, Brian Wai1, Ron Blankstein2, Suhny Abbara1, Udo Hoffmann1 and Brian B. Ghoshhajra1|
|1Cardiac MR PET CT Program, Division of Cardiology and Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, USA|
|2Department of Medicine (Cardiovascular Division) and Radiology, Brigham and Women’s Hospital, Boston, USA|
|Corresponding Author :||Leif-Christopher Engel
Cardiac MR PET CT Program
Division of Cardiology and Department of Radiology
Massachusetts General Hospital and Harvard Medical School
Cambridge St, Suite 400 Boston, USA
E-mail: [email protected]
|Received March 22, 2012; Accepted May 13, 2012; Published May 18, 2012|
|Citation: Engel LC, Ferencik M, Liew GY, Karolyi M, Sidhu MS, et al (2012) Ultra-Low Dose Cardiac CT Angiography at 80 kV using Second Generation Dual- Source CT: Assessment of Radiation Dose and Image Quality. J Med Diagn Meth 1:104. doi:10.4172/2168-9784.1000104|
|Copyright: © 2012 Engel LC, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.|
Objectives: We sought to determine the feasibility of using 80 kV in clinical cardiac CTA, by comparing radiation doses and image quality versus standardized 100 kV protocols.
Methods: In this retrospective study, a tube potential of 80 kV was used in 40 consecutive patients (BMI 22.6 ± 2.8). 40 matched patients (BMI 23.1 ± 2.8) were scanned with a tube potential of 100 kV and served as the control group. Qualitative and quantitative image quality parameters were determined in the proximal and distal segments of the coronary arteries.
Results: Similar subjective image quality scores were seen between the two protocols. The mean CNR and SNR were at 100 kV vs 80 kV (CNR 19.9 ± 6.0 vs 15.7 ± 5.5; p<0.01 and SNR 17.7 ± 5.5 vs 14.4 ± 4.9). The median radiation dose for the 80 kV protocol was significantly lower compared to the 100 kV protocol (83.0 mGy x cm [58.0- 134.0] vs 193.0 mGy x cm [108.5-225.0]; p<0.01)
Conclusion: A tube potential of 80 kV is feasible and results in a radiation dose reduction of 57% compared to 100 kV protocols while preserving subjective image quality.