alexa Undiagnosed COPD in Patients with Established Cardiovascular Diseases:Prevalence, Symptoms Profiling and Functional Status | OMICS International | Abstract
ISSN: 2161-105X

Journal of Pulmonary & Respiratory Medicine
Open Access

Like us on:

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Undiagnosed COPD in Patients with Established Cardiovascular Diseases:Prevalence, Symptoms Profiling and Functional Status

Li-Cher Loh1*, Narentharen Selvarajah1, Shanthiny Mohan1, Wai-Sun Choo1 and Ismail Omar2

1Department of Medicine, Penang Medical College, Penang, Malaysia

2Department of Cardiology, Penang Hospital, Penang, Malaysia

*Corresponding Author:
Li-Cher Loh
Professor of Medicine & Head
Department of Medicine
Penang Medical College, 4 Jalan Sepoy Lines
Penang, 10450 Malaysia
Tel: 604 226 3459
Fax: 604 227 6529
E-mail: [email protected] edu.my

Received date: August 08, 2011; Accepted date: November 06, 2011; Published date: November 08, 2011

Citation: Loh LC, Selvarajah N, Mohan S, Choo WS, Omar I (2011) Undiagnosed COPD in Patients with Established Cardiovascular Diseases: Prevalence, Symptoms Profiling and Functional Status. J Pulmonar Respirat Med 1:107. doi: 10.4172/2161-105X.1000107

Copyright: © 2011 Loh LC, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Background: COPD is associated with cardiovascular co-morbidities. We examined the prevalence of undiagnosed COPD in our local population of patients with stable cardiovascular diseases and the profile of their respiratory symptoms and functional status.

Methods: Eligible patients with established stable cardiovascular diseases were prospectively recruited from the cardiology outpatient clinic of an urban-based university teaching hospital and evaluated with pre- and post- bronchodilator spirometry testing and interview using standard questionnaire.

Results: Of the 501 subjects recruited, 113 (22.6%) had COPD defined on post-bronchodilator fixed FEV 1 /FVC ratio <70%. 109 (96.5%) had moderate severity while only 4 (3.5%) had severe disease by GOLD classification. Compared to non-COPD, proportionately more COPD patients were older, males, exposed to cigarette smoking (including passive smoking) and had congestive cardiac failure and pulmonary hypertension. Also proportionately more COPD subjects had more cough, sputum and dyspnoae, and poorer scores in MRC dyspnoae scale, NYHA functional class and SGRQ quality of life. These symptoms were generally worst in the evening. They also had significantly higher mean number of unscheduled visits to outpatient clinics, emergency departments and of hospital admissions over the past 12 months. After multivariate analysis, only dyspnoae [odd ratio (95%CI): 4.2 (1.8-9.7); p=0.001] and cigarette smoking [2.8 (1.1-6.80); 0.018] remained independently associated with COPD.

Conclusions: A significant proportion of patients with established cardiovascular diseases have undiagnosed COPD of moderate severity. Dyspnoae and cigarette smoking appear highly predictive of COPD.

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
Leave Your Message 24x7