alexa Unforeseen Pseudotumoral Colitis in Deceased Donor with Carbon Monoxide Intoxication | OMICS International | Abstract
ISSN: 2161-0495

Journal of Clinical Toxicology
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Case Report

Unforeseen Pseudotumoral Colitis in Deceased Donor with Carbon Monoxide Intoxication

Cristian Lupascu1, Raluca Neagu Movila2, Delia Rusu Andriesi1, Ana-Maria Trofin1, Mihaela Blaj3, Corina Lupascu-Ursulescu4*, Mihai Danciu5

1Department of Surgery, Surgical Unit 1, University of Medicine and Pharmacy, Grigore T. Popa, University Hospital St. Spiridon Iasi, Romania

2Transplant Coordinator, University Hospital St. Spiridon Iasi Romania

3Department of Intensive Care and Anesthesiology, University of Medicine and Pharmacy, Grigore T. Popa, University Hospital, St. Spiridon Iasi Romania

4Department of Radiology, University of Medicine and Pharmacy, Grigore T. Popa, University Hospital St. Spiridon Iasi, Romania

5Department of Pathology, University of Medicine and Pharmacy, Grigore T. Popa, University Hospital St. Spiridon Iasi, Romania

*Corresponding Author:
Corina Lupascu-Ursulescu
Department of Radiology
University of Medicine and Pharmacy
Grigore T. Popa, University Hospital
St. Spiridon Iasi, Romania
Tel: 0040 744 70 96 80
E-mail: [email protected]

Received date: January 24, 2015; Accepted date: February 22, 2015; Published February 28, 2015

Citation: Cristian Lupascu, Raluca Neagu Movila, Delia Rusu Andriesi, Ana-Maria Trofin, Mihaela Blaj, et al. (2015) Unforeseen Pseudotumoral Colitis in Deceased Donor with Carbon Monoxide Intoxication. J Clin Toxicol 5:231. doi: 10.4172/2161-0495.1000231

Copyright: © 2015 Cristian Lupascu, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Carbon monoxide intoxication is a well-known cause of hypoxic injury primarily to the central nervous system and myocardium, but the bowel may be also vulnerable. Patients succumbing to carbon monoxide poisoning are usually considered unsuitable for organ procurement and they are routinely rejected in many transplant centers. As the organ supply is by far insufficient to meet the needs of patients from the waiting lists for transplant, there is a greater effort to increase the donor organ pool. Therefore special attention is being devoted to such “marginal” or “high-risk “donors. Similarly, tumors revealed during organ procurement require careful consideration in the evaluation of organ donors and transplant recipients. We herein report a multiorgan procurement from a victim of carbon monoxide poisoning who underwent a prolonged cardiopulmonary resuscitation and was intraoperatively diagnosed with a right colon tumor. Intraoperative frozen section examination ruled out malignancy and revealed an acute ischemic colitis. It is suggested that patients dying of carbon monoxide poisoning who are considered appropriate donors, may have intraoperatively revealed pseudotumoral ischemic colitis which does not preclude multiorgan procurement.

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