Unusual Case of Post-Infection Nephritis Associated with Nephrin Mutation
- *Corresponding Author:
- Osamay Safdar
Pediatirc Nephrology Unit, College of Medicine
King Abdulaziz University, Saudi Arabia
Tel: +966 800 116 9528
E-mail: [email protected]
Received Date: December 23, 2016; Accepted Date: January 23, 2017; Published Date: January 28, 2017
Citation: Safdar O, Alaifan B, Turkistany A, Mokhtar G, Aldesoky S (2017) Unusual Case of Post-Infection tNephritis Associated with Nephrin Mutation. J Clin Case Rep 7:918. doi: 10.4172/2165-7920.1000918
Copyright: © 2017 Safdar O, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
NPHS1 gene is the gene responsible for production of Nephrin, which has role in the structure of glomerular filtration barrier. Nephrin located in slit diaphragm, which has a role in preventing passage of plasma proteins out of glomerular capillaries.