alexa Update on Genetics of Leprosy
ISSN: 2329-8731

Journal of Infectious Diseases & Preventive Medicine
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Review Article

Update on Genetics of Leprosy

Susilene Maria Tonelli-Nardi1*, Carla Renata Graça2 and Vânia Del´ArcoPaschoal3

1 Centro de Laboratório Regional – Instituto Adolfo Lutz - São José do Rio Preto, São Paulo, Brasil

2 Laboratório de Investigação Neuromuscular- LIN, Faculdade de Medicina de São José do Rio Preto, São Paulo, FAMERP, Brasil

3 Profa. Dra. Adjunta do departamento de enfermagem, Faculdade de Medicina de São José do Rio Preto, São Paulo, FAMERP, Brasil

*Corresponding Author:
Susilene Maria Tonelli Nardi
Centro de Laboratório Regional – Instituto Adolfo Lutz - São José do Rio Preto, São Paulo, Brasil
Tel: 17-91054399
E-mail: [email protected]

Received Date: June 27, 2013; Accepted Date: April 08, 2014; Published Date: April 10, 2014

Citation: Tonelli-Nardi SM, Graça CR, Paschoal VD (2014) Update on Genetics of Leprosy. J Anc Dis Prev Rem 2:109. doi: 10.4172/2329-8731.1000109

Copyright: © 2014 Tonelli-Nardi SM, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Leprosy is a chronic granulomatous infectious disease caused by Mycobacterium leprae that mainly infects skin macrophages and Schwann cells in peripheral nerves. Genetic and environmental factors play an important role in leprosy. It is estimated that approximately 90% of the population develop protective immunity in infection, and, therefore, do not get sick. Other individuals, however, show clinical susceptibility to a wide spectrum of pathogens associated to changes in immune response. Data observed in various populations show that some aspects related to disease progression are due to host genetic factors that influence control of the initial infection and the host immune response to that infection. Nevertheless, individual genetic factors have a strong influence on the acquisition of or protection against leprosy, since the limited genetic diversity observed among M. leprae strains is not a significant factor for the development and the clinical course of disease.


Share This Page

Additional Info

Loading Please wait..
Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals


[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version