Updates on Hepato-Renal Syndrome
Kyota Fukazawa * and H Thomas Lee
Department of Anesthesiology, College of Physicians and Surgeons of Columbia University, NY, USA
- *Corresponding Author:
- Kyota Fukazawa
Department of Anesthesiology
College of Physicians and Surgeons of Columbia University
630 West 168th St, New York, NY 10032-3784, USA
E-mail: [email protected]
Received Date: August 16, 2013; Accepted Date: September 25, 2013; Published Date: September 27, 2013
Citation: Fukazawa K, Lee HT (2013) Updates on Hepato-Renal Syndrome. J Anesth Clin Res 4:352. doi: 10.4172/2155-6148.1000352
Copyright: © 2013 Fukazawa K, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Hepato-Renal Syndrome (HRS) is one of the most detrimental conditions in patients with end stage liver failure. Historically, HRS was considered a terminal disease associated with cirrhosis and was termed “liver-death syndrome”. Furthermore, despite the improved understanding of pathophysiology and the reversibility of renal dysfunction in HRS, mortality remains extremely high especially for type 1 HRS. This review summarizes the recent advances in the pathophysiology, diagnosis and management of HRS and also provides an evolving area of research in the pathophysiologic mechanisms of HRS, which may open the door for new therapeutic approaches.