alexa Upper Limb DVT in an Oncological Patient with a PICC Treated with Edoxaban: A Case Report | OMICS International| Abstract
ISSN: 2165-7831

Journal of Blood & Lymph
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  • Case Report   
  • J Blood Lymph 2018, Vol 1(1): 004
  • DOI: 10.4172/2165-7831.S1-004

Upper Limb DVT in an Oncological Patient with a PICC Treated with Edoxaban: A Case Report

Pierpaolo Di Micco1*, Gianluca Di Micco2, Lucrezia Amoroso3* and Corrado Lodigiani3
1Department of Medicine, UOC Internal Medicine, Ospedale Fatebenefratelli di Napoli, Italy
2Department of Medicine, UO Cardiology, Ospedale Fatebenefratelli di Napoli, Italy
3Thrombosis Center, Istituto Clinico Humanitas “IRCCS”, Rozzano, Milano, Italy
*Corresponding Author : Pierpaolo Di Micco, UOC Internal Medicine, Fatebenefratelli Hospital of Naples, Italy, Tel: 393398 078146, Email: [email protected]ibero.itt

Received Date: Jul 12, 2018 / Accepted Date: Jul 20, 2018 / Published Date: Jul 26, 2018


Upper extremities deep venous thrombosis (UEDVT) is less frequent than lower limb DVT but the incidence of UEDVT may be increased in patients affected by malignancies and bearing central venous catheters (CVC) or other devices as peripherally inserted central catheters (PICC). The standard of care for the treatment of cancer-related venous thromboembolism has been low molecular weight heparin (LMWH) for several years. But treatment with direct oral anticoagulants (DOACs) may represent an alternative to LMWH in patients with cancer related VTE. In the present article, we report a case of a 49 year old man with colorectal cancer in treatment with chemotherapy who presented DVT of the upper left limb with involvement of subclavian-axillar venous axis. Patient was treated with edoxaban 60 mg following a few days of LMWH (i.e., 100 u/kg twice daily). After three months, a vascular ultrasound scan showed the disappearance of DVT with a full recanalization of the vessel.

Keywords: Deep venous thrombosis; VTE; Antithrombotic treatment; Edoxaban; Chemotherapy

Citation: Di Micco P, Micco GD, Lodigiani C (2018) Upper Limb DVT in an Oncological Patient with a PICC Treated with Edoxaban: A Case Report. J Blood Lymph S1: 004. Doi: 10.4172/2165-7831.S1-004

Copyright: © 2018 Di Micco P, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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