alexa Use of 10% Lipid Emulsion to Reverse Ventricular Fibrillation Following Of an Iatrogenic Local Anesthetic Overdose: A Case Report
ISSN : 2153-2435

Pharmaceutica Analytica Acta
Open Access

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Research Article

Use of 10% Lipid Emulsion to Reverse Ventricular Fibrillation Following Of an Iatrogenic Local Anesthetic Overdose: A Case Report

Alexandre de Araujo Altamiranda1, Raphaella Amanda Maria Leite Fernandes1, Ana Maria Menezes Caetano1, Fernanda Lobo Lago Flores1 and Flavia Augusta de Orange2*

1Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil

2Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Recife, Pernambuco, Brazil

*Corresponding Author:
Flavia Augusta de Orange
Anesthesiologist
Instituto de Medicina Integral Prof. Fernando Figueira (IMIP)
Recife, Pernambuco, Brazil
Tel: 55-8121224122
Fax: 55-8121224122
E-mail: [email protected]

Received Date: June 16, 2015; Accepted Date: July 24, 2015; Published Date: July 27, 2015

Citation: Altamiranda AdA, Fernandes RAML, Caetano AMM, Flores FLL, de Orange FA (2015) Use of 10% Lipid Emulsion to Reverse Ventricular Fibrillation Following Of an Iatrogenic Local Anesthetic Overdose: A Case Report. Pharm Anal Acta 6:398. doi: 10.4172/2153-2435.1000398

Copyright: © 2015 Altamiranda AdA, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Local anesthetic systemic toxicity (LAST) is a potentially fatal complication. Recognition of its occurrence, appropriate treatment and post-LAST care are essential to ensure a favorable outcome. This report describes the use of a lipid emulsion therapy (10% Lipovenos® emulsion), in a 41-year old woman, who inadvertently received cardioplegia following administration of 0.5% bupivacaine directly into the coronary ostium during extracorporeal circulation for aortic valvuloplasty. Although there have been no reports recommending its use for the pharmacological treatment of LAST to reversed toxicity, 10% lipid emulsion therapy may represent a viable alternative to the use of 20% lipid emulsion.

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