alexa Use of Pharmacogenetic Testing in Routine Clinical Practice Improves Outcomes for Psychiatry Patients
ISSN: 2378-5756

Journal of Psychiatry
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Use of Pharmacogenetic Testing in Routine Clinical Practice Improves Outcomes for Psychiatry Patients

Timothy Ramsey1,2*, Elizabeth Griffin3, Qian Liu4, Mark D Brennan1 and Sandeep Vaishnavi3,5

1SureGene, LLC 600 Envoy Circle Louisville, Kentucky, USA.

2Clinical Reference Laboratories, Lenexa, Kansas, USA.

3The Neuropsychiatric Clinic [NPC] at Carolina Partners, North Carolina, USA.

4HTG Molecular Inc, Tucson, Arizona, USA.

5Department of Community and Family Medicine, Duke University Medical Center, Durham, North Carolina, USA.

*Corresponding Author:
Timothy Ramsey
Head of Behavioral Health
Clinical Reference Laboratory
600 Envoy Circle, Louisville
KY 40299, USA
Tel: 317-501-5785
E-mail: [email protected]

Received Date: November 14, 2015; Accepted Date: July 06, 2016; Published Date:July 13, 2016

Citation: Ramsey T, Griffin E, Liu Q, Brennan MD, Vaishnavi S (2016) Use of Pharmacogenetic Testing in Routine Clinical Practice Improves Outcomes for Psychiatry Patients? J Psychiatry 19:377. doi:10.4172/2378-5756.1000377

Copyright: © 2016 Ramsey T, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Introduction: In clinical trials, pharmacogenetic testing has been shown to improve outcomes in psychiatric patients. It is unclear if these improved outcomes translate into routine clinical practice. A significant impediment to evaluation of pharmacogenetics testing in routine practice has been a lack of quantifiable outcomes data. This study leverages longitudinal symptom evaluations using validated computer-based assessments to evaluate the impact of pharmacogenetic testing across a number of psychiatric symptom dimensions in routine clinical practice.
Methods:
This study retrospectively evaluated data from The Neuropsychiatric Clinic, Carolina Partners, Raleigh, NC who were either tested (n=74) or untested (n=57) with a commercial genetic test at physician’s discretion. All subjects had at least four evaluations with the NeuroPsych Questionnaire-Short Form. Treatment effects were estimated using a general linear model incorporating all time points and baseline values for the 12 NPQ individual items.
Results:
Tested patients experienced significantly greater improvement over time in a number of symptom dimensions. Aggression, anxiety, depression, fatigue, impulsivity, mood instability, panic, and suicide symptoms improved more in tested patients compared to untested patients (p=10-8 to 10-20).
Conclusions: In routine clinical practice, pharmacogenetic testing can enable significant improvement in clinically outcomes for psychiatric patients with a variety of diagnoses.

Keywords

Share This Page

Additional Info

Loading
Loading Please wait..
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords