alexa Use of STOPP/ START Criteria to Perform Active Pharmacovigilance in the Elderly
ISSN: 2329-6887

Journal of Pharmacovigilance
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Research Article

Use of STOPP/ START Criteria to Perform Active Pharmacovigilance in the Elderly

Cecilia Maldonado, Marta Vázquez*, Natalia Guevara and Pietro Fagiolino
Pharmaceutical Sciences Department, Faculty of Chemistry, Universidad de la República, Montevideo, Uruguay
Corresponding Author : Marta Vázquez
Faculty of Chemistry, Avenida General Flores 2124
P.O. Box 1157, 11800 Montevideo, Uruguay
Tel: (598) 2 2097899 (int 215)
E-mail: [email protected]
Received August 19, 2014; Accepted October 01, 2014; Published October 10, 2014
Citation: Maldonado C, Vázquez M, Guevara N, Fagiolino P (2014) Use of STOPP/ START Criteria to Perform Active Pharmacovigilance in the Elderly . J Pharmacovigilance 2:146. doi: 10.4172/2329-6887.1000146
Copyright: © 2014 Maldonado C, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Background: Inappropriate prescription of drugs is common in the elderly and contributes to an increased risk of adverse drug reactions. Several tools have been developed to detect potentially inappropriate prescription but the STOPP (Screening Tool of Older Persons’ potentially inappropriate Prescriptions) and START (Screening Tool to Alert doctors to Right Treatment) criteria resulted better than others to identify medicines that lead to negative outcomes. The purpose of this work was to study the prevalence of Potentially Inappropriate Medicines and Potential Prescribing Omissions in Uruguayan hospitalized elderly patients using these criteria.

Methods: A cross-sectional study was carried out in different Services of the University Hospital. STOPP and START criteria were applied to identify inappropriate medicines or omissions.

Results: Potentially Inappropriate medicines identified by STOPP represent 21.2% of the total prescriptions (862) and Potential Prescribing Omissions identified by START account for the 5.7%.

Conclusions: Using STOPP-START criteria could be a useful tool to improve prescription in the elderly and can contribute to the rational use of medicines in this age group.


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