alexa Uterine Artery Doppler in Women with History of Previous Pre Eclampsia and Women with Chronic Hypertension: Re-evaluation of a Prognostic Value in a High-Risk Population | Abstract
ISSN: 2161-0932

Gynecology & Obstetrics
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Research Article

Uterine Artery Doppler in Women with History of Previous Pre Eclampsia and Women with Chronic Hypertension: Re-evaluation of a Prognostic Value in a High-Risk Population

Woschitz MC*, Idris T*, Csapo B, Haas J, Ulrich D, Lang U and Cervar-Zivkovic M

Department of Gynecology and Obstetrics, Medical University Graz, Austria

*Corresponding Author:
Manuela Claudia Woschitz
Department of Gynecology and Obstetrics
Medical University Graz, Austria
E-mail: [email protected]
Tina Idris
Department of Gynecology and Obstetrics
Medical University Graz, Austria
Tel: +43 316 385-80828
E-mail: [email protected]

Received Date: December 10, 2014; Accepted Date: February 02, 2014; Published Date: February 06, 2014

Citation: Woschitz MC, Idris T, Csapo B, Haas J, Ulrich D, et al. (2014) Uterine Artery Doppler in Women with History of Previous Pre Eclampsia and Women with Chronic Hypertension: Re-evaluation of a Prognostic Value in a High-Risk Population. Gynecol Obstet (Sunnyvale) 4:206. doi: 10.4172/2161-0932.1000206

Copyright: © 2014 Woschitz MC, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Objective: To evaluate the prognostic role of uterine artery Doppler for pre-eclampsia in high-risk patients. Because of the higher prevalence of new onset of disease in a high-risk population, a better performance could be expected in this special group.

Methods: This retrospective study compares uterine artery Doppler to predict pre-eclampsia in patients with a history of pre-eclampsia and also in patients with chronic hypertension, both with high-risk to develop recurrent, superimposed or new onset pre eclampsia. Doppler measurements of uterine arteries were performed every 4 weeks in the 1st and 2nd trimester.

Results: Pre-eclampsia occured in 33% of current high-risk pregnancies. The best performance of pre eclampsia was provided by bilateral notching plus increased PI ≥ 2.5, both in the 1st and 2nd trimester. In the 1st trimester the specifity was 81% (95% CI: 58-95) in the Prior PE group and 95% (95% CI: 74-100) in the C. H. group. In the 2nd trimester the sensitivity was 97% (95% CI: 86-100) in the Prior PE group and 100% (95% CI: 93 100) in the C. H. group. Sensitivity was very low in the 1st and 2nd trimester.

Conclusion: Our results show, that the negative predictive value of uterine artery Doppler works well even in a high risk group. Data however suggest relative poor positive predictive value of uterine artery Doppler even in a high-risk population using a cut-off of 2.5 PI. A value of the uterine artery Doppler using a high cut-off might be in the increased specifity. Nevertheless, a combination of the uterine artery Doppler with biochemical markers and maternal parameters seems to be essential.

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