Uterus and Cervix Metastasis of Lung Cancer: A Case ReportChun-Yao Huang1, YI-Hsin Lee2, Lim Kun Eng3and Yao-Kuang Wu1,4,*
- *Corresponding Author:
- Yao-Kuang Wu
Division of Pulmonary Medicine
Taipei Tzu-Chi Hospital
Buddhist Tzu-Chi Medical Foundation
No. 289, Jianguo Road, Xindian City
New Taipei City, Taiwan, Republic of China
Tel: +886-2-6628-9779, extn. 5709
E-mail: [email protected]
Received date: July 27, 2015; Accepted date: August 18, 2015; Published date: August 24, 2015
Citation:Huang CY, Lee YH, Eng LK, Wu YK (2015) Uterus and Cervix Metastasis of Lung Cancer: A Case Report. J Pulm Respir Med 5:282. doi:10.4172/2161-105X.1000282
Copyright: ©2015 Huang CY, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
A 57-year-old, postmenopausal woman was diagnosed with lung adenocarcinoma, T4N3M1b, stage IV with brain and bone metastases, in 2008. Five years following of chemotherapy and target therapy (Epidermal Growth Factor Receptor Inhibitors), the patient complained of increasing problems with lower abdominal pain, urination incontinence and abnormal vaginal bleeding. The magnetic resonance imaging examination revealed only infiltrative soft tissue tumor in the uterus, whole layered and extrauterine extension with urinary bladder involvement. There were no other abnormalities noted in the pelvic area such as colon, rectum or urological tract. Histological and immunohistochemical examinations of endocervical and endometrial biopsies revealed metastatic adenocarcinoma, with the staining reactivity as primary lung neoplasm. This is the first report of coincident metastases endometrium and cervix from primary lung cancer.