alexa Validation of EGOS-600 Near Infrared Spectroscopy to Measure Cerebral Oxygen Saturation by Comparing to NIRO-200nx In Vitro and In Vivo
ISSN: 2155-9880

Journal of Clinical & Experimental Cardiology
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Validation of EGOS-600 Near Infrared Spectroscopy to Measure Cerebral Oxygen Saturation by Comparing to NIRO-200nx In Vitro and In Vivo

Ding Han1, Hui Zhang2, Bai-Yu Tian3, Yan Zhu3, Dan Zhang3, Yue Li4, Yi-Chao Teng4, Hong Gu3, Xu Meng3, Yi Luo1, De-Ming Zhu5* and Jia Li2*

1Department of Anesthesia, Capital Institute of Paediatrics, Beijing, PR. China

2Clinical Physiology Research Laboratory, Capital Institute of Paediatrics, Beijing, PR. China

3Beijing Anzhen Hospital Affiliated to Capital Medical University, Beijing, PR. China

4School of Medicine, Tsinghua University, Beijing, PR. China

5Extracorporeal Circulation Department, Shanghai Children's Medical Center, Shanghai, PR. China

*Corresponding Authors:
Jia Li
Clinical Physiology Research Laboratory
Capital Institute of Pediatrics, 2 Yabao Street
Chaoyang District, Beijing, PR. China
Tel: 010-85628194
Fax: 010-85628194
E-mail: [email protected]
 
De-Ming Zhu
Extracorporeal Circulation Department
Shanghai Children's Medical Center, Shanghai, PR. China
Tel: +86-21-38626161
E-mail: [email protected]

Received date: April 7, 2016; Accepted date: April 26, 2016; Published date: April 30, 2016

Citation: Han D, Zhang H, Tian B, Zhu Y, Zhang D, et al. (2016) Validation of EGOS-600 Near Infrared Spectroscopy to Measure Cerebral Oxygen Saturation by Comparing to NIRO-200nx In Vitro and In Vivo. J Clin Exp Cardiolog 7:440. doi:10.4172/2155-9880.1000440

Copyright: © 2016 Han D, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Objective: Near-infrared spectroscopy (NIRS) has been increasingly used to monitor regional cerebral oxygen saturation (rScO2) during cardiac surgery and intensive care. NIRO-200nx (Hamamatsu Phototonics, Japan) is one of widely used NIRS devices. EGOS-600 is a new device developed by Tsinghua University in China. We validated EGOS-600 by comparing to NIRO-200nx in laboratory and clinical settings.
Materials and methods: Laboratory test : A liquid tissue model was made consisting of 40 ml of human whole blood, 25 ml intralipid-20% and 935 ml buffer solution. Oxygen saturation (SO2) levels ranging 20-100% were made by inflating oxygen or adding sodium hydrosulfite. Eleven pairs of measures were obtained using the two oximeters.
Clinical test: 31 children (aged 0.7-61 months, median 11 months) and 20 adults (aged 18-73 years, median 59 years) were enrolled within one week after cardiac surgery. One probe of each device was sequentially placed at the middle of patient’s forehead to measure rScO2 at 2-3 hour intervals. One hundred pairs of rScO2 were obtained in each group. Bland-Altman method was used for data analysis. Results: Laboratory test showed a bias of-2% and limits of agreement 20 to-24% with a trend of overestimating SO2 by EGOS-600 when average SO2>50% and underestimating when <50%. This trend disappeared in patients. The bias was-5.9% in children and-4.1% in adults. The limits of agreement were 1.3 to-13.1% in children, and 3.3 to-11.5% in adults.
Conclusions: EGOS-600 introduces a small underestimation of rScO2 when compared to NIRO-200nx, with acceptable limits of agreement. The new device is applicable in clinical settings in both children and adults.

Keywords

Share This Page

Additional Info

Loading
Loading Please wait..
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords