alexa Variations in the Number of Circulating Tumor Cells Dur
[Jurnalul de Chirurgie]
ISSN: 1584-9341

Journal of Surgery
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Variations in the Number of Circulating Tumor Cells During the Surgical Sequence for Locally Advanced Rectal Cancer

Dragoș-Viorel Scripcariu1,2,*, Gabriel Dimofte1 and Dan Ferariu3

1Department of Surgery, Grigore T Popa University of Medicine and Pharmacy, Iași, Romania

21st Surgical Unit, Regional Institute of Oncology, Iași, Romania

3Department of Pathology, Regional Institute of Oncology, Iași, Romania

*Corresponding Author:
Scripcariu Dragoș-Viorel
Assistant Lecturer, PhD student
Department of Surgery, Faculty of Medicine
Grigore T Popa University of Medicine and Pharmacy
Iași, Romania, 700483
Tel: +40(0)723913425
E-mail: [email protected]

Received date: December 22, 2016; Accepted date: December 27, 2016; Published date: January 02, 2017

Citation: Scripcariu DV, Dimofte G, Ferariu D. Variations in the Number of Circulating Tumor Cells During the Surgical Sequence for Locally Advanced Rectal Cancer. Journal of Surgery [Jurnalul de chirurgie]. 2017; 13(1): 31-34 DOI: 10.7438/1584-9341-13-1-6

Copyright: © 2017 Scripcariu DV, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Aim: This study aims to assess the variation of the levels of circulating tumor cells during surgical manipulation, by in vivo evaluation at three key points during treatment. Materials and methods: This was a pilot study with 20 included patients with mid and low locally advanced rectal cancer, with neoadjuvant treatment. The device used to evaluate the number of circulating tumor cells in the bloodstream of the patients was the “Detektor Cancer” GILUPI Cell Collector®. The tests were performed at 8 weeks after the end of the neoadjuvant treatment, at three key moments: in the preoperative period, during surgery - after the surgical dissection and at 7 days postoperatively. Results: There was an increase in the number of circulating tumor cells after the surgical sequence, but no statistical significance could be achieved due to the small number of patients included in the study. Conclusion: The circulating tumor cell number is a useful biomarker for the prognosis of the patients with colorectal cancer, demonstrated through several studies. However, there is need for standardization in this field of research. Our study, although with visible differences between the preoperative, intraoperative and postoperative values, showed no statistical significance.

Keywords

Share This Page

Additional Info

Loading
Loading Please wait..
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords