alexa Varicocele and Male Infertility: Evidence in the Era of
ISSN: 2161-038X

Reproductive System & Sexual Disorders: Current Research
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Editorial

Varicocele and Male Infertility: Evidence in the Era of Assisted Reproductive Technology

Eric Chung1,2*

1 University of Queensland, Department of Urology, Princess Alexandra Hospital, Brisbane QLD, Australia

2 St Andrew’s Pelvic Medicine Centre, St Andrew’s War Memorial Hospital, Brisbane QLD, Australia

*Corresponding Author:
Eric Chung
Department of Urology
Princess Alexandra Hospital
Brisbane QLD Australia
Tel: +61733242468
Fax: +61733242546
E-mail: [email protected]

Received date: December 27, 2013; Accepted date: December 31, 2013; Published date: January 07, 2014

Citation: Chung E (2014) Varicocele and Male Infertility: Evidence in the Era of Assisted Reproductive Technology. Reprod Syst Sex Disord 3:e114. doi:10.4172/2161-038X.1000e114

Copyright: © 2014 Chung E. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Purpose: To evaluate the current literature on the varicocele treatment and impact on fertility. Materials and Methods: Pertinent articles were identified through PubMed search on varicocele repair and male infertility. Discussion: The proposed mechanisms of how varicocele results in impaired spermatogenesis and infertility include an altered or impaired testicular blood flow, increased scrotal temperature and oxidative stress as well as resulting sex hormone changes, reflux of adrenal hormones, and autoimmunity with anti-sperm antibody formation. The repair of varicocele as an infertility treatment is dependent on many factors such as the grade and size of the varicocele, unilateral or simultaneous bilateral repair, female partner’s age, the period during which the couple as failed to conceive and quality of the semen. Summary: Varicoceles can present in up to 40% of men presenting with infertility and published literature support the findings that varicocele adversely affect spermatogenesis. Surgical varicocelectomy is an effective treatment for improving the semen parameters in men and spontaneous pregnancy rate for couples with an infertile male partner who has low semen parameters and a palpable varicocele. Comparative studies favour the microsurgical subinguinal technique as the standard of care with highest rates of success and lowest rates of complications.

Share This Page

Additional Info

Loading
Loading Please wait..
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords