alexa Venous Thromboembolism in Brain Tumor Patients: A Review of Literature | OMICS International
ISSN: 2329-8790

Journal of Hematology & Thromboembolic Diseases
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Review Article

Venous Thromboembolism in Brain Tumor Patients: A Review of Literature

David J. Cote and Timothy R. Smith*
Department of Neurosurgery, Brigham and Women’s Hospital, Boston, MA, USA
Corresponding Author : Timothy R. Smith
Department of Neurosurgery
Brigham and Women’s Hospital
15 Francis Street – PBB3, Boston, MA-02115, USA
Tel: +617 525 8371
Fax: +617 734 8342
E-mail: [email protected]
Received February 20, 2015; Accepted March 12, 2015; Published March 18, 2015
Citation: Cote DJ, Smith TR (2015) Venous Thromboembolism in Brain Tumor Patients: A Review of Literature . J Hematol Thrombo Dis 3:196. doi:10.4172/2329-8790.1000196
Copyright: © 2015 Cote DJ, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
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Abstract

Venous thromboembolism (VTE) is a relatively common and well-described condition, affecting approximately 1-2% of the general population. VTE can lead to significant morbidity and death via pulmonary embolism (PE). During the post-operative period, VTE occurs at higher rates due to natural thrombotic responses to injury and limited post-operative mobility. In general, rates of post-operative VTE are higher in patients undergoing operations for cranial and spinal lesions than for lesions of other types, a phenomenon that is not fully explained. Several studies have demonstrated that other risk factors for VTE include age, sex, ethnicity, hospital stay length, and coagulation state. Aggressive chemical and mechanical measures for VTE prophylaxis are indicated in the postoperative period to prevent the formation of VTE. Here we review the literature on VTE in brain tumor patients, with a focus on their etiology, diagnosis, treatment, and prophylaxis.

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