alexa Ventilator-Associated Pneumonia Caused by Pseudomonas aeruginosa in Intensive Care Unit: Epidemiology and Risk Factors | OMICS International | Abstract
ISSN: 2161-0703

Journal of Medical Microbiology & Diagnosis
Open Access

Like us on:

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Ventilator-Associated Pneumonia Caused by Pseudomonas aeruginosa in Intensive Care Unit: Epidemiology and Risk Factors

Enrico Raineri1*, Laura Porcella2, Annamaria Acquarolo2, Luciano Crema1, Fulvio Albertario1and Andrea Candiani2

1Servizio di Rianimazione, Intensive Care and Neuroanaesthesia Institutes Hospital of Cremona, Italy

2Institute of Anesthesiology and Intensive Care, Civil Hospital, University of Brescia, Italy

*Corresponding Author:
Enrico Raineri
Service of Intensive Care
Intensive Care and Neuroanaesthesia Institutes Hospital of Cremona
vialeConcordia 1, 26100 Cremona, Italy
Tel: 3477504042
E-mail: [email protected]

Received Date: February 06, 2014; Accepted Date: July 22, 2014; Published Date: July 24, 2014

Citation: Raineri E, Porcella L, Acquarolo A, Crema L, Albertario F, et al. (2014) Ventilator-Associated Pneumonia Caused by Pseudomonasaeruginosa in Intensive Care Unit: Epidemiology and Risk Factors. J Med Microb Diagn 3:149. doi: 10.4172/2161-0703.1000149

Copyright: © 2014 Raineri E, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Purpose: We studied the risk factors for the acquisition of Ventilator-associated Pneumonia (VAP) caused by Pseudomonas aeruginosa in two Intensive Care Units (ICU).

Methods: We carried out a case-control study, from January 1, 2006 through June 30, 2008. We defined as CASES patients with Pseudomonas aeruginosa VAP and CONTROLS patients with VAP caused by other Gramnegative bacteria.

Results: The study of risk factors for the development of VAP by Pseudomonas aeruginosa showed that three of them are referred to the pre-ICU admission history of the patient: hospitalization during previous 6 months, admission from other wards/hospitals instead of domicile provenance (p<0.01) and duration of pre-ICU hospitalisation (p<0.01, at multivariate analysis: OR 2.09 IC95% 1.18-3.72). Analysis of antibiotic prescription before the development of VAP showed as independent risk factor the number of different antibiotic classes prescribed to patients or rather the complexity of antibiotic exposure (OR 2.3 IC95% 1.14-4.67). Analysis of mortality revealed a non-significant difference between VAP caused by Pseudomonas or other Gram-negative bacteria, although our data suggest an association between MDR Pseudomonas infection and higher mortality (p=0.03).

Conclusion: Our study offers points that can contribute to improve the empiric antibiotic prescription in ICU. In presence of in-hospital patients presenting with a previous history of antibiotic prescription, with a complex clinical condition preceding ICU admission or with a prolonged ventilatory assistance, presenting with signs or symptoms of infection, should be advisable to prescribe a therapy with a specific activity against Pseudomonas aeruginosa.

Keywords

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
Leave Your Message 24x7