Virus-Induced Autophagy in Innate ImmunityHongjing Gu, Xiliang Wang and Penghui Yang*
Beijing Institute of Microbiology and Epidemiology, Beijing, China
- *Corresponding Author:
- Penghui Yang
302 Military Hospital
Beijing Institute of Microbiology and Epidemiology
E-mail: [email protected]
Received date: April 25, 2014; Accepted date: August 20, 2014; Published date: August 28, 2014
Citation: Gu H, Wang X, Yang P (2014) Virus-Induced Autophagy in Innate Immunity. Clin Microbial 3:165. doi: 10.4172/2327-5073.1000165
Copyright: © 2014 Gu H, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
When a virus invades a host cell, autophagy is triggered to maintain cellular homeostasis. Virus-induced autophagy is a double-edged sword in the antiviral function of host innate immunity. Unlike apoptosis, autophagy plays a different role in cell survival or inducing cell death. This mini-review summarizes recent developments in our understanding of the antiviral roles of autophagy in host innate immunity.