Vitamin D Status in Egyptian Children and Adolescents with Type 1 Diabetes MellitusMona M Hassan1, Abeer A Alashmawy1, Sahar A Sharaf2, Hend M Soliman1*, Ziad M Abu Fares1 and Imad M Abuanza1
- *Corresponding Author:
- Hend Mehawed Abdel Latif Soliman
Lecturer of Pediatrics and Pediatric Endocrinology
Kasr-Al-Aini School of Medicine
Cairo University, Post Box 2398, Cairo
E-mail: [email protected]
Received date: June 20, 2015; Accepted date: January 07, 2016; Published date: January 15,2016
Citation: Hassan MM, Alashmawy AA, Sharaf SA, Soliman HM, Fares ZMA, et al. (2016) Vitamin D Status in Egyptian Children and Adolescents with Type 1 Diabetes Mellitus. J Diabetes Metab 6: 636. doi:10.4172/2155-6156.1000636
Copyright: © 2016 Hassan MM, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Introduction: Vitamin D is an important factor for bone health especially in type 1 DM (T1DM). Thus, optimal supply of vitamin D may be of particular importance for bone health in children and adolescents with T1DM. Objective: To assess the vitamin D status in children and adolescents with T1DM and to study related factors that may influence serum vitamin D level. Methods: Sixty (30 prepubertal, 30 pubertal) Egyptian children and adolescents with T1DM were enrolled in this cross-sectional study, the mean age for the prepubertal group was 6.85 ± 1.64 years and for the pubertal group was 14.43 ± 1.524 years. Detailed history and complete physical examination laying stress on the sun exposure, skin color, exercise and detailed dietetic history. Dietary content of calcium (mg/day) and vitamin D (IU/day) were calculated. Laboratory assessment included serum calcium, phosphorus, 25-hydroxy-vitamin D (25OHD) and parathormone (PTH). Results: Most of the study group (91.67 %) was vitamin D deficient. There was no significant correlation between serum vitamin D and serum calcium, phosphorus, parathormone, anthropometric measures, duration of diabetes, mean HbA1c, insulin dose, and sun exposure. Despite the high prevalence of vitamin D deficiency, there was a low prevalence of secondary hyperparathyroidism (11.67%) in the study group. Conclusion: Prevalence of vitamin D deficiency in diabetic children and adolescents is very high but underestimated. Therefore, screening and supplementation of vitamin D should be considered.