alexa Voriconazole used for Treatment of Tracheobronchial Aspergillosis: A Report of Two Cases
ISSN: 2167-0870

Journal of Clinical Trials
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Case Report

Voriconazole used for Treatment of Tracheobronchial Aspergillosis: A Report of Two Cases

Chang Ran Zhang, Ming Li*, Jian Cong Lin*, Wen Ming XU*, Yuan Yuan Niu and Hui Shao Ye
Huang Pu Hospital of the First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510700, China
Corresponding Authors : Jian Cong Lin
Huang Pu Hospital of the First Affiliated Hospital
Sun Yat-sen University
Guangzhou 510700, China
Tel: 86-020- 82379627
E-mail: [email protected]
  Ming Li
Huang Pu Hospital of the First Affiliated Hospital
Sun Yat-sen University
Guangzhou 510700, China
Tel: 86-020-82379627
  Wen Ming XU
Huang Pu Hospital of the First Affiliated Hospital
Sun Yat-sen University
Guangzhou 510700, China
Tel: 86-020-82379627
Received May 15, 2012; Accepted June 25, 2012; Published July 02, 2012
Citation: Zhang CR, Li M, Lin JC, Wen Ming XU, Niu YY, et al. (2012) Voriconazole used for Treatment of Tracheobronchial Aspergillosis: A Report of Two Cases. J Clin Trials 2:117. doi:10.4172/2167-0870.1000117
Copyright: © 2012 Zhang CR, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Tracheobronchial aspergillosis mainly involves the trachea, primary bronchus and segmental bronchus. The main symptoms including dyspnea, asthma and cough. Bronchoscopic findings supply the main evidence for diagnosis. Voriconazole has been widely used as azole antifungal agent in recent years, which is also a first-line drug in the treatment of invasive pulmonary aspergillosis (IPA), but rare report exists in the treatment of tracheobronchial aspergillosis. Two patients have been remitted with Voriconazole in this study, and it was found that Voriconazole could improve therapeutic effect and shorten therapeutic time with less adverse effects.

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