Watch Out for the Unexpected: Sole Gallbladder Metastasis in a Patient with Malignant Melanoma Striked by FDG-PETOkuyucu Kursat1, Alagoz Engin1, Arslan Nuri1*, Komurcu Seref2, Ayan Asli`1 and Ozturk Erkan3
- *Corresponding Author:
- Nuri Arslan
Department of Nuclear Medicine
Gulhane Military Medical Academy
and Medical Faculty, Ankara, Turkey
Tel: + 903123044801;
E-mail: [email protected]
Received date: December 31, 2014, Accepted date: Jan 31, 2015, Published date: February 03, 2015
Citation: Kursat O, Engin A, Nuri A, Seref K, Erkan O (2015) Watch Out for the Unexpected:Sole Gallbladder Metastasis in a Patient with Malignant Melanoma Striked by FDG-PET. J Nucl Med Radiat Ther 6:210. doi:10.4172/2155-9619.1000210
Copyright: © 2015 Kursat O, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Metastatic gallbladder disease is a rare pathology. Gallbladder metastasis of malignant melanoma is especially rarer. Herein we present the solitary metastasis of a malignant melanoma to the gallbladder. 47-year old male having an ulcerated skin lesion at right toe was diagnosed as malignant melanoma with excisional biopsy. Thereon the patient without locoregional disease was treated with large surgical resection. A metastatic inguinal lymph node was excised 4 months later and interferon-alpha treatment was begun. FDG-PET imaging was requested to evaluate the extent of disease after 15 days and any metastatic focus was not detected. A control FDG-PET was performed for the evaluation of therapy 8 months later. There was only an unexpected, markedly increased focal FDG uptake arousing doubt in the gallbladder fossa on the whole-body images. This accumulation was proven histopathologically as malignant melanoma metastasis after exploratory cholecystectomy and the patient was treated by dacarbazine+cisplatin. Physicians interpreting FDG-PET scans of patients with malignant melanoma must be cautious about the significance of prominent unusual uptakes at unexpected localizations. It is mandatory to establish a certain histopathologic diagnosis if possible.