alexa Worsening Muscle Weakness in Myasthenia Gravis Patient Suffering Dengue Infection
ISSN: 2329-891X

Journal of Tropical Diseases & Public Health
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Case Report

Worsening Muscle Weakness in Myasthenia Gravis Patient Suffering Dengue Infection

Hardjo Lugito NP1*, Margaret2, Andree Kurniawan1 and Merlyn Tjiang1

1Internal Medicine Department, Faculty of Medicine, Pelita Harapan University, Indonesia

2Siloam Karawaci General Hospital, Indonesia

*Corresponding Author:
Nata Pratama Hardjo Lugito
Internal Medicine Department
Faculty of Medicine
Pelita Harapan University, Indonesia
Tel: 622154210130
E-mail: [email protected], [email protected]

Received date: April 10, 2014; Accepted date: May 24, 2014; Published date: May 27, 2014

Citation: Hardjo Lugito NP, Margaret, Kurniawan A, Tjiang M (2014) Worsening Muscle Weakness in Myasthenia Gravis Patient Suffering Dengue Infection. J Trop Dis 2:140. doi:10.4172/2329-891X.1000140

Copyright: © 2014 Hardjo Lugito NP, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



The dengue infection is the second most common mosquito-borne disease affecting human beings. Dengue can manifest with a wide range of neurological features, which have been noted - depending on the clinical setting in 0.5-21% of patients with dengue admitted to hospital. Neuromuscular complication can manifest in muscle weakness, which can be found in forms of myalgia, myositis to rhabdomyolysis, Guillain – Barre syndrome and hypokalemia. The pathogenesis and also the role of host and virus in dengue neuromuscular complications were not clear. In this case report, a 36 year-old female MG patient suffered from dengue infection. The MG symptoms worsen and then improved along with the course of dengue. There was a possibility that muscle weakness in this patient were related to dengue disease as the symptoms improved along with the resolving dengue, but the mechanism could be associated with virus neurotropic effect, systemic infection effect or immune mediated.

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