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ISSN: 2376-0427

Journal of Pigmentary Disorders
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Review Article

Xeroderma Pigmentosum-A Rare Genodermatosis: Overview of Literature

Shamimul Hasan1* and Shazina Saeed2
1Department of Oral Medicine and Radiology, Faculty of dentistry, Jamia Millia Islamia, New Delhi, India
2Amity Institute of Public Health, Amity University, Noida, UP, India
Corresponding Author : Shamimul Hasan
Department of Oral Medicine and Radiology
Faculty of Dentistry, Jamia Millia Islamia, New Delhi, India
Tel: 09953290676
E-mail: shamim0571@
Received November 10, 2015; Accepted December 07, 2015; Published December 12, 2015
Citation: Hasan S, Saeed S (2015) Xeroderma Pigmentosum-A Rare Genodermatosis: Overview of Literature. Pigmentary Disorders 2:230. doi:10.4172/2376-0427.1000230
Copyright: © 2015 Hasan S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Xeroderma pigmentosum is a rare genodermatosis, autosomal recessive in nature in which excessive ultraviolet radiation causes skin, ocular, neurological, and oral lesions along with development of cutaneous and internal malignancies at an early age. There is no definitive cure for the disease. Avoidance of ultraviolet radiation, use of protective clothing, sunscreens, oral retinoids, 5-fluorouracil and regular consultations with dermatologists, ophthalmologists, neurologists and dentists forms an important part of the treatment protocol. This paper aims to throw light on the etiopathogenesis, clinical features and treatment modalities of this life threatening disease. There is also a special mention on the oral manifestations and dental health considerations of the rare disorder.


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