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Young Male with Secondary Acute Hemophagocytic Lymphohistiocytosis | OMICS International | Abstract
ISSN: 2471-8556

Oncology & Cancer Case Reports
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Case Report

Young Male with Secondary Acute Hemophagocytic Lymphohistiocytosis

Neeraj Kumar Tulara*
Dr LH Hiranandani Hospital, Hillside Avenue, Hiranandani Gardens, Powai, Mumbai, India
*Corresponding Author : Neeraj Kumar Tulara
Dr LH Hiranandani Hospital,Hillside Avenue
Hiranandani Gardens, Powai, Mumbai 400076, India
Tel: +91-9833552955
E-mail: [email protected]
Received: February 24, 2016; Accepted: March 07, 2016; Published: March 10, 2016
Citation: Tulara NK (2016) Young Male with Secondary Acute Hemophagocytic Lymphohistiocytosis. Oncol Cancer Case Rep 2:111. doi:10.4172/occrs.1000111
Copyright: © 2016 Tulara NK. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Hemophagocytic lymphohistiocytosis (HLH), also known as hemophagocytic syndrome (HPS), is a rare life threatening hematologic disorder manifested by clinical findings of extreme inflammation and unregulated immune activation. HLH can occur as a familial or sporadic disorder, and it can be triggered by a variety of events that disrupts immune haemostasis. Infection is a common trigger both in those with a genetic predisposition and in sporadic cases. Often the greatest barrier to a successful outcome is delay in diagnosis, which is difficult because of the rarity of this syndrome. Here we, present a case of a young male who presented with enteric fever and confirmed as acute hemophagocytic syndrome and deteriorated rapidly inspite of quick diagnosis and treatment.